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# Weekly · Oct 5: Drugs for CKD and Dialysis, the Heart on Dialysis, and a Camera for Fistulas
- URL: https://nephspace.com/weekly-oct-5/
- Published: 2026-10-05T10:00:00.000Z
- Updated: 2026-10-05T09:59:59.000Z
- Description: Five new papers for the commute, the run or the couch: a statin gap in CKD, GLP-1 drugs on dialysis, the heart on dialysis, troponin on the move, and an AI for fistulas.
- Author: Dr Wael Hussein
- Tags: Episodes, Dialysis, CKD and cardiometabolic, Other, #weekly, #has-audio, #tr-04a7b4cc

A new lipid guideline makes reduced kidney function a reason for a statin; in 2024, before it arrived, most patients for whom kidney function is now the reason had no statin prescription. An editorial asks whether GLP-1 drugs belong in dialysis units before the trials are done. A review says dialysis adequacy should be measured by what it does for the heart, troponin turns out to be a moving target during a session, and an AI reads photos of fistulas. Five picks from the week of September 25, 2026, each with the background, what's new, the caveats and what it means on Monday.

**Disclosure:** Dr. Hussein serves on the Fresenius Medical Care US Home Medical Advisory Board. Two papers in this episode have Fresenius ties: a review with coauthors affiliated with Fresenius Medical Care that rates hemodiafiltration (Fresenius makes hemodiafiltration equipment), and an AI tool from the Renal Research Institute, which authors' disclosure forms describe as a wholly owned Fresenius subsidiary. Dr. Csaba Kovesdy, author of the GLP-1 editorial, is Dr. Hussein's department chief.

## Chapters

- **01:37** Statins in CKD · [Read the story](https://nephspace.com/statin-gap-ckd-2026-guideline/)
- **06:18** GLP-1 drugs on dialysis · [Read the story](https://nephspace.com/glp1-ra-dialysis-kovesdy-editorial/)
- **10:17** Beyond Kt/V · [Read the story](https://nephspace.com/beyond-ktv-dialysis-adequacy-heart/)
- **15:21** Troponin during dialysis · [Read the story](https://nephspace.com/troponin-i-during-dialysis-review/)
- **19:21** Fistula aneurysms and AI · [Read the story](https://nephspace.com/ai-photo-classifier-fistula-aneurysms/)

## Papers in this episode

- Kim M, et al. Lipid-Lowering Therapy in Individuals with CKD. CJASN 2026 (ahead of print, research letter). [Link](https://doi.org/10.2215/CJN.0000001218?ref=nephspace.com)
- Kovesdy CP. Glucagon-Like Peptide-1 Receptor Agonists in Dialysis: The Evidence Grows, but Trials Must Follow. CJASN 2026 (ahead of print, editorial). [Link](https://doi.org/10.2215/CJN.0000001256?ref=nephspace.com)
- The editorial discusses Karpinski S, et al. Glucagon-Like Peptide-1 Receptor Agonist Use and Risks of Hospitalization and Mortality in Patients with End-Stage Kidney Disease. CJASN 2026\. [Link](https://doi.org/10.2215/CJN.0000001208?ref=nephspace.com) (figures in this episode are as the editorial reports them).
- Zoccali C, et al. Beyond Kt/V: Redefining Dialysis Adequacy as Targeted Cardiovascular Risk Reduction. Nephrol Dial Transplant 2026 (advance article). [Link](https://doi.org/10.1093/ndt/gfag223?ref=nephspace.com)
- Jørgensen JF, et al. The Intradialytic Changes in Cardiac Troponin I — A Systematic Review. Semin Dial 2026 (open access). [Link](https://doi.org/10.1111/sdi.70049?ref=nephspace.com)
- Dong Z, et al. Cloud-Based AI Application for Classifying Arteriovenous Hemodialysis Vascular Access Aneurysms. CJASN 2026 (ahead of print, open access). [Link](https://doi.org/10.2215/CJN.0000001231?ref=nephspace.com)

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*Physician-led, AI-assisted. Dr. Wael Hussein chooses the papers, reviews and edits every script, and approves every episode. AI (Claude, by Anthropic) writes the first draft from the full text of each paper, and a separate AI check compares every number with the papers; Dr. Hussein then reviews and edits the draft before the AI hosts (ElevenLabs) voice it. Everything is summarized in our own words. For education and information only, not medical advice. Please talk to your own physician or care team about your health. Clinicians: read the original before changing practice. See our [disclaimer](https://nephspace.com/disclaimer/). Views are the creator's own and not those of his employer. No sponsors.*